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COLTS VS CHARGERS PREDICTION: WHO WILL HAVE THE EDGE BETWEEN INDY'S TAYLOR AND LA'S UNHERALDED NEW BACK?

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  Sunday, October 20, 2025 | SoFi Stadium Two Rising Teams Leading Their Divisions Clash in One of the NFL's Biggest Games Two teams on the rise and leading their respective divisions square off Sunday when the Colts visit the Chargers in one of the biggest games on the NFL slate. COLTS VS CHARGERS: THE KEY STATS Los Angeles Chargers are favored to beat the Indianapolis Colts winning 55.1% of pre-game simulations by the Opta supercomputer Since 2005 the Colts are 2-8 against the Chargers – that .200 winning percentage is their lowest against any AFC team in that span The Colts have scored points on their last 59 red-zone drives – one shy of the 2013-14 Denver Broncos for the longest such streak by any team in the last 30 years TWO TEAMS ON THE RISE Six weeks into the 2025 NFL season and the AFC is as wide open as ever with some regular contenders looking vulnerable – as well as looking up in the standings. Two teams however that are on the rise and sitting atop their...